Description

n-(2-Benzoylmercaptopropionyl)Glycine-D3 Ethyl Ester CAS NO 1189930-99-1 is a high-purity, deuterium-labeled derivative of a mercaptopropionyl glycine ethyl ester, serving as a critical stable isotope-labeled intermediate. This compound is essential for advanced research and development, providing the isotopic purity required for precise analytical and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in drug discovery, pharmacokinetics, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a deuterated internal standard for the accurate quantification of its non-labeled counterpart or related metabolites in complex biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Bioanalytical Method Development: Critical for developing and validating sensitive and specific mass spectrometry-based assays in pharmaceutical analysis.
• Stable Isotope Labeling in Medicinal Chemistry: Serves as a building block for synthesizing deuterium-labeled drug candidates to study isotope effects or improve metabolic profiles.
• Metabolomics and Proteomics Research: Facilitates quantitative analysis in systems biology studies aiming to understand disease mechanisms.
• Quality Control Reference Material: Acts as a certified reference standard for ensuring the accuracy and reliability of analytical results in GLP/GMP environments.

Basic Information

Product Name	n-(2-Benzoylmercaptopropionyl)Glycine-D3 Ethyl Ester
CAS No.	1189930-99-1
Molecular Formula	C15H14D3NO5S
Molecular Weight	Contact for details
Synonyms	Glycine, N-[2-[(benzoylthio)methyl]-1-oxo-3,3,3-trideuteriopropyl]-, ethyl ester; Ethyl N-(2-(benzoylthio)methyl-3,3,3-trideuterio-1-oxopropyl)glycinate; Benzoylmercaptopropionylglycine Ethyl Ester-d3; Bz-MPG Ethyl Ester-d3; Deuterated Tiopronin Ethyl Ester Derivative; 2-Benzoylmercaptopropionylglycine Ethyl Ester-d3; Acetadote-d3 Ethyl Ester Analog; Stable Isotope Labeled Mercaptopropionyl Glycine Ester
EINECS	Contact for details

Quality Control

Every batch of n-(2-Benzoylmercaptopropionyl)Glycine-D3 Ethyl Ester is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure exceptional isotopic and chemical purity. Our quality assurance protocol is designed to meet the stringent requirements of research and regulatory standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications for isotopic enrichment, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.