Description

R,S Equol 4’-Sulfate Sodium Salt is a chemically defined, high-purity reference standard and research-grade metabolite of the soy isoflavone daidzein. This compound is critical for analytical and pharmacological research, providing a standardized material for method development, validation, and biological studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories focusing on phytoestrogen metabolism, bioavailability, and biomarker analysis.

Application

• Analytical Reference Standard: Used as a primary standard for the quantitative and qualitative analysis (e.g., HPLC, LC-MS/MS) of equol sulfate metabolites in biological matrices like plasma, urine, and tissues.
• Pharmacokinetic & Metabolism Studies: Essential for investigating the absorption, distribution, metabolism, and excretion (ADME) profiles of equol and its conjugated forms in preclinical and clinical research.
• Biomarker Research: Serves as a critical calibrator in developing assays to measure equol sulfate as a biomarker for dietary soy intake and individual metabolic capacity (equol-producer status).
• Enzyme Activity Assays: Employed as a substrate or standard in studies of sulfotransferase (SULT) and other conjugation enzyme activities.
• In Vitro Biological Testing: Used to study the biological activity, receptor binding affinity, and potency of sulfated vs. unsulfated phytoestrogen metabolites.
• Nutraceutical & Pharmaceutical Development: Supports research into the development of standardized nutraceutical formulations and novel therapeutics targeting estrogen-related pathways.

Basic Information

Product Name	R,S Equol 4’-Sulfate Sodium Salt
CAS No.	1189685-28-6
Molecular Formula	C15H15NaO6S
Molecular Weight	346.33 g/mol
Synonyms	Equol 4'-Sulfate Sodium Salt; (±)-Equol 4'-Sulfate Sodium Salt; 3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol 4'-(Hydrogen Sulfate) Sodium Salt; 7-Hydroxy-3-(4-sulfooxyphenyl)-2,3-dihydrochromen-4-one Sodium Salt; Sodium Equol Sulfate; Racemic Equol Sulfate Sodium Salt; Equol Sulfate Conjugate Sodium Salt
EINECS	Contact for details

Quality Control

Our R,S Equol 4’-Sulfate Sodium Salt is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Identity and purity are confirmed by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the product label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.