Description

Hydantoin-4,5-13C2,1-15N is a stable isotope-labeled analog of the heterocyclic compound hydantoin, specifically enriched with carbon-13 at the 4 and 5 positions and nitrogen-15 at the 1 position. This compound is an essential internal standard and tracer in advanced analytical research, enabling precise quantification and metabolic pathway elucidation. It is primarily required by researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for applications in mass spectrometry, NMR spectroscopy, and stable isotope probing studies.

Application

• Internal Standard for Quantitative Analysis: Used as a high-purity reference standard in LC-MS and GC-MS methods for the accurate quantification of hydantoin and its derivatives in complex matrices.
• Metabolic Pathway Tracing: Serves as a crucial tracer in drug metabolism and pharmacokinetic (DMPK) studies to track the fate of active pharmaceutical ingredients and their metabolites.
• NMR Spectroscopy Studies: Enables detailed structural and dynamic analysis in nuclear magnetic resonance due to its distinct isotopic signature, reducing signal overlap.
• Proteomics and Biomarker Research: Facilitates the development of stable isotope labeling by amino acids in cell culture (SILAC) and other quantitative proteomic techniques.
• Environmental Fate Studies: Applied in agrochemical research to study the degradation, transformation, and environmental fate of pesticides and herbicides.
• Synthesis of Labeled Compounds: Acts as a key synthetic building block for preparing more complex molecules labeled with stable isotopes for research and diagnostic purposes.

Basic Information

Item	Detail
Product Name	Hydantoin-4,5-13C2,1-15N
CAS No.	1189495-02-0
Molecular Formula	C313C2H4N215NO2
Molecular Weight	104.06 g/mol (for labeled form)
Synonyms	1,3-Diazinane-2,4,5-trione-4,5-13C2,1-15N; 2,4-Imidazolidinedione-4,5-13C2,1-15N; Glycolylurea-4,5-13C2,1-15N; Hydantoic acid amide-4,5-13C2,1-15N; Ureidoacetamide-4,5-13C2,1-15N; [4,5-13C2,1-15N]-Hydantoin; Carbon-13, Nitrogen-15 labeled Hydantoin; Isotopically Labeled Hydantoin
EINECS	Contact for details

Quality Control

Every batch of Hydantoin-4,5-13C2,1-15N is manufactured and tested under strict quality management systems to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical identity. Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and analytical methods are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (chemical purity)
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 99 atom % 15N
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.