Description

p-Tyramine-D4 Hydrochloride is a stable isotope-labeled analog of tyramine, where four hydrogen atoms are replaced by deuterium, making it an essential internal standard for precise quantitative analysis. This high-purity compound is critical for ensuring accuracy and reliability in sophisticated analytical techniques, particularly in metabolomics and neurotransmitter research. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in advanced biochemical studies and method development.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in quantitative bioanalytical assays.
• Metabolomics research for the accurate quantification of tyramine and related biogenic amines.
• Neurotransmitter pathway studies and pharmacokinetic/pharmacodynamic (PK/PD) modeling.
• Stable Isotope Dilution Mass Spectrometry (SID-MS) for high-precision measurement.
• Quality control and method validation in pharmaceutical development and manufacturing.
• Biochemical research investigating trace amine-associated receptors (TAARs).

Basic Information

Product Name	p-Tyramine-D4 Hydrochloride
CAS No.	1188266-06-9
Molecular Formula	C8D4H7NO • HCl
Molecular Weight	171.65 g/mol
Synonyms	4-(2-Aminoethyl)phenol-2,3,5,6-d4 hydrochloride; Deuterated Tyramine Hydrochloride; 4-Hydroxyphenethylamine-d4 hydrochloride; (2,3,5,6-D4)-4-(2-Aminoethyl)phenol hydrochloride; Tyramine-d4 HCl; p-Tyramine-2,3,5,6-d4 hydrochloride; 2-(4-Hydroxyphenyl)ethylamine-d4 hydrochloride
EINECS	Contact for details

Quality Control

Our p-Tyramine-D4 Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical purity. A detailed Certificate of Analysis (COA) is provided, reporting key parameters such as assay, isotopic purity, and impurity profile to ensure it meets the exacting standards required for analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.