Description

(R)-1,1'-Binaphthyl-2,2'-Disulfonyl Dichloride is a high-purity, chiral sulfonyl chloride derivative, a critical building block in asymmetric synthesis and pharmaceutical research. Its value lies in its role as a versatile chiral auxiliary and resolving agent, enabling the creation of enantiomerically pure compounds essential for advanced drug development. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fine chemical industries for the synthesis of chiral ligands, catalysts, and active pharmaceutical ingredients (APIs).

Application

• As a chiral derivatizing agent for the resolution of racemic mixtures of amines, alcohols, and other functional groups.
• In the synthesis of chiral sulfonamide ligands for asymmetric catalysis, including hydrogenation and cross-coupling reactions.
• As a key intermediate for constructing enantiomerically pure binaphthyl-based frameworks used in molecular recognition and sensor technology.
• For the preparation of pharmaceutical intermediates where the introduction of a chiral, bulky sulfonyl group is required.
• In academic and industrial research exploring new methodologies in stereoselective synthesis.
• As a precursor for high-performance materials with specific optical properties.

Basic Information

Product Name	(R)-1,1'-Binaphthyl-2,2'-Disulfonyl Dichloride
CAS No.	1187629-43-1
Molecular Formula	C₂₀H₁₂Cl₂O₄S₂
Molecular Weight	443.34 g/mol
Synonyms	(R)-BINOL-2,2'-Disulfonyl Dichloride; (R)-2,2'-Bis(chlorosulfonyl)-1,1'-binaphthyl; (R)-1,1'-Bi-2-naphthol-2,2'-disulfonyl Dichloride; (R)-BINOL Disulfonyl Dichloride; (R)-BINSA Dichloride; (R)-2,2'-Dichlorosulfonyl-1,1'-binaphthyl; (R)-1,1'-Binaphthalene-2,2'-disulfonyl Dichloride
EINECS	Contact for details

Quality Control

Our (R)-1,1'-Binaphthyl-2,2'-Disulfonyl Dichloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.