Description

Methyl 3-Bromo-5-Fluoro-2-Methylbenzoate is a high-purity, multi-functional benzoate ester derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its precise molecular architecture, featuring bromo and fluoro substituents that enable selective chemical transformations for creating complex target molecules. This intermediate is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require reliable, high-quality raw materials for drug discovery and active ingredient development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the halogenated aromatic core contributes to biological activity and environmental stability.
• Material Science Research: Serves as a precursor for synthesizing specialty monomers and ligands used in polymer chemistry and catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 3-Bromo-5-Fluoro-2-Methylbenzoate
CAS No.	1187318-53-1
Molecular Formula	C10H10BrFO2
Molecular Weight	261.09 g/mol
Synonyms	3-Bromo-5-fluoro-2-methylbenzoic acid methyl ester; Methyl 3-bromo-5-fluoro-o-toluate; Benzoic acid, 3-bromo-5-fluoro-2-methyl-, methyl ester; 2-Methyl-3-bromo-5-fluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-5-Fluoro-2-Methylbenzoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We are committed to meeting the stringent requirements of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.