Description

(2R)-1-(11Br)-(Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl)-2-Methyl-1,2,3,4-Tetrahydroquinoline, 98% is a high-purity, chiral organophosphorus compound featuring a complex dinaphthodioxaphosphepin scaffold. This advanced intermediate is critical for its role in asymmetric catalysis, particularly in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and pharmaceutical R&D departments developing novel synthetic methodologies and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Catalysis: Serves as a key chiral ligand or precursor for transition metal catalysts in enantioselective synthesis.
• Pharmaceutical Research & Development: An essential building block for the discovery and synthesis of novel, optically active drug candidates.
• Methodology Development: Used by academic and industrial chemists to develop new catalytic reactions and study stereochemical outcomes.
• Fine Chemical Synthesis: Employed in the production of high-value, complex chiral molecules for agrochemicals and specialty materials.
• Ligand Library Construction: A valuable component for creating diverse ligand libraries to screen for new catalytic activities.

Basic Information

Product Name	(2R)-1-(11Br)-(Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl)-2-Methyl-1,2,3,4-Tetrahydroquinoline, 98%
CAS No.	1186392-43-7
Molecular Formula	C31H23BrNO2P
Molecular Weight	552.40 g/mol
Synonyms	(2R)-2-Methyl-1-(4-((11bR)-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl))-1,2,3,4-tetrahydroquinoline; (R)-2-Methyl-1-((R)-4-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)-1,2,3,4-tetrahydroquinoline; Br-DTBM-SEGPHOS; DTBM-SEGPHOS bromide derivative; Chiral dinaphthodioxaphosphepin ligand; Brominated SEGPHOS-type ligand
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.