Description

4-Fluoro-2-Formylbenzoic Acid is a high-value fluorinated aromatic building block that combines a carboxylic acid and an aldehyde functional group on a benzene ring. This unique bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists developing specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the preparation of monomers for specialty polymers, such as polyimides or liquid crystals, where fluorine improves thermal and chemical resistance.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes due to its reactive aldehyde group for conjugation.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences industry.

Basic Information

Item	Details
Product Name	4-Fluoro-2-Formylbenzoic Acid
CAS No.	1186047-15-3
Molecular Formula	C8H5FO3
Molecular Weight	168.12 g/mol
Synonyms	2-Formyl-4-fluorobenzoic Acid; 4-Fluoro-2-carboxybenzaldehyde; 4-Fluorophthalaldehydic Acid; 4-Fluoroisophthalaldehydic Acid; 2-Carboxy-4-fluorobenzaldehyde; 4-Fluoro-1,2-benzenedicarboxaldehyde, 1-carboxylic acid; 1186047-15-3; 4-Fluorobenzaldehyde-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2-Formylbenzoic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods like HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.