Description

5,6-Dimethoxy-1-Indanone-13C3 is a stable isotope-labeled analog of 5,6-Dimethoxy-1-indanone, where three carbon atoms are replaced with the carbon-13 isotope. This compound is essential for use as an internal standard in quantitative mass spectrometry, providing unmatched accuracy and reliability in analytical measurements. It is primarily required by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in advanced pharmacokinetic, metabolic, and proteomic studies.

Application

• Quantitative Mass Spectrometry: Serves as a critical internal standard for the precise quantification of the unlabeled parent compound in complex biological matrices like plasma, urine, and tissue homogenates.
• Drug Metabolism and Pharmacokinetics (DMPK): Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Biomarker Analysis: Used in the development and validation of LC-MS/MS assays for endogenous metabolites or disease biomarkers, ensuring measurement precision.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities or degradation products during drug development and quality control.
• Proteomics and Metabolomics Research: Facilitates stable isotope dilution techniques for the absolute quantification of proteins, peptides, and small molecules in systems biology studies.
• Environmental and Forensic Analysis: Applied in trace analysis for environmental monitoring or forensic toxicology where high specificity and accuracy are mandated.

Basic Information

Item	Details
Product Name	5,6-Dimethoxy-1-Indanone-13C3
CAS No.	1185155-55-8
Molecular Formula	C11H12O3 (with three 13C atoms)
Molecular Weight	~207.2 g/mol (exact mass depends on 13C enrichment)
Synonyms	1-Indanone, 5,6-dimethoxy-, (13C3); 5,6-Dimethoxyindan-1-one-13C3; 13C3-Labeled 5,6-Dimethoxy-1-indanone; 5,6-Dimethoxy-2,3-dihydro-1H-inden-1-one-13C3; Isotopically labeled 5,6-Dimethoxyindanone; 13C3-5,6-Dimethoxy-1-indanone; 5,6-Dimethoxy-1-indanone (13C3)
EINECS	Contact for details

Quality Control

Every batch of 5,6-Dimethoxy-1-Indanone-13C3 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive characterization by NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, isotopic enrichment, and absence of unlabeled material.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.