Description

3-[2-[(Diaminomethylene)Amino-4-Thiazolyl]Thio]Propionitrile-13C3 is a stable isotope-labeled compound, specifically a carbon-13 (13C) labeled analog of a key thiazole derivative. This product is essential for use as an internal standard in quantitative mass spectrometry, enabling highly accurate and sensitive analytical measurements. It is primarily required by pharmaceutical and biotechnology research organizations for drug metabolism and pharmacokinetics (DMPK) studies, proteomics, and other advanced analytical applications where precise quantification is critical.

Application

• Internal Standard for Liquid Chromatography-Mass Spectrometry (LC-MS/MS) in bioanalytical method development and validation.
• Quantitative analysis in Drug Metabolism and Pharmacokinetics (DMPK) studies for tracking parent compounds and metabolites.
• Use in Proteomics and Metabolomics research for accurate relative and absolute quantification of biomolecules.
• Isotope dilution mass spectrometry for achieving regulatory compliance in pharmaceutical impurity profiling and assay development.
• High-purity reference material for method calibration in contract research organizations (CROs) and analytical laboratories.
• Critical reagent in the synthesis of isotopically labeled active pharmaceutical ingredients (APIs) or advanced intermediates.

Basic Information

Product Name	3-[2-[(Diaminomethylene)Amino-4-Thiazolyl]Thio]Propionitrile-13C3
CAS No.	1185040-73-6
Molecular Formula	C313C3H8N4S2
Molecular Weight	~203.25 g/mol (for 13C3 labeled form)
Synonyms	3-[2-[(Diaminomethylene)amino-4-thiazolyl]thio]propionitrile-13C3; 2-Amino-α-(aminomethylene)-4-thiazolepropanenitrile-13C3; 3-[(2-Amino-4-thiazolyl)(imino)methyl]amino]-3-thiopropanenitrile-13C3; 13C3-Labeled Thiazole Nitrile Derivative; Isotope Labeled Internal Standard 1185040-73-6; Carbon-13 Labeled Propionitrile Thiazole; (Amino(2-amino-4-thiazolyl)methylene)amino]-3-thiopropanenitrile-13C3
EINECS	Contact for details

Quality Control

Our stable isotope-labeled compounds are produced and tested under stringent conditions to ensure the highest isotopic purity and chemical integrity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing chemical purity (by HPLC), isotopic enrichment, and other critical parameters. We adhere to cGMP principles for manufacturing, ensuring traceability and consistency suitable for regulatory submission support.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C. The product is light-sensitive and should be handled accordingly to maintain its stability and isotopic integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Enrichment	≥ 99% 13C3
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.