Description

5-(2-Chlorophenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique halogenated structure makes it a valuable precursor for developing active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to create novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in the development of small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials requiring specific fluorinated motifs.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Organic Synthesis Building Block: Provides a versatile scaffold for further functionalization in complex multi-step synthetic routes.

Basic Information

Product Name	5-(2-Chlorophenyl)-2-Fluorobenzoic Acid
CAS No.	1184837-79-3
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	2'-Chloro-2-fluorobiphenyl-4-carboxylic Acid; 2-Fluoro-5-(2-chlorophenyl)benzoic Acid; 4-Carboxy-2'-chloro-2-fluorobiphenyl; [1,1'-Biphenyl]-4-carboxylic acid, 2'-chloro-2-fluoro-; 2-Fluoro-5-(o-chlorophenyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 5-(2-Chlorophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.