Description

5-Fluoro-2-(Trifluoromethyl)Cinnamic Acid is a high-value fluorinated cinnamic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl groups, makes it indispensable for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the fluorine atoms improve lipophilicity and biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystal materials.
• Chemical Biology Probe Development: Employed to synthesize fluorinated analogs of natural products for structure-activity relationship (SAR) studies.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or emissive layer materials in electronic displays.

Basic Information

Product Name	5-Fluoro-2-(Trifluoromethyl)Cinnamic Acid
CAS No.	1184721-90-1
Molecular Formula	C10H6F4O2
Molecular Weight	234.15 g/mol
Synonyms	(E)-3-[5-Fluoro-2-(trifluoromethyl)phenyl]acrylic acid; 3-(5-Fluoro-2-(trifluoromethyl)phenyl)-2-propenoic acid; 5-Fluoro-α-methyl-2-(trifluoromethyl)cinnamic acid (common name); 2-Propenoic acid, 3-[5-fluoro-2-(trifluoromethyl)phenyl]-, (2E)-; FTCA (abbreviation); 5-F-2-TFMCA
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Trifluoromethyl)Cinnamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and process development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.