Description

2-Fluoro-5-(3-Methoxyphenyl)Benzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical pharmaceutical intermediate and organic building block. Its unique structure, featuring both fluorine and methoxy substituents, makes it invaluable for modulating the biological activity and physicochemical properties of target molecules in drug discovery. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances bioavailability and stability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and biological pathways.
• Advanced Material Development: A monomer or modifier in the synthesis of specialty polymers and liquid crystals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2-Fluoro-5-(3-Methoxyphenyl)Benzoic Acid
CAS No.	1184619-67-7
Molecular Formula	C14H11FO3
Molecular Weight	246.23 g/mol
Synonyms	5-(3-Methoxyphenyl)-2-fluorobenzoic Acid; 2-Fluoro-5-(3-methoxyphenyl)benzoic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 2'-fluoro-5'-methoxy-; 2'-Fluoro-5'-methoxy[1,1'-biphenyl]-3-carboxylic Acid; 2-Fluoro-5-(3-methoxy-phenyl)-benzoic acid; Benzoic acid, 2-fluoro-5-(3-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-5-(3-Methoxyphenyl)Benzoic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay and impurity profiles. Our quality commitment supports applications requiring GMP-grade intermediates and reliable supply for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.