Description

2-Amino-5-Chloro-3-Fluoro-Benzoic Acid Methyl Ester is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring amino, chloro, fluoro, and ester functionalities, makes it a versatile intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzoic acid ester scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogen and amino groups contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex dyes and organic pigments due to its aromatic amine structure.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to create biaryl and other complex structures.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags used in biochemical research and diagnostics.

Basic Information

Product Name	2-Amino-5-Chloro-3-Fluoro-Benzoic Acid Methyl Ester
CAS No.	1184597-61-2
Molecular Formula	C8H7ClFNO2
Molecular Weight	203.60 g/mol
Synonyms	Methyl 2-Amino-5-Chloro-3-Fluorobenzoate; 5-Chloro-3-Fluoroanthranilic Acid Methyl Ester; 2-Amino-5-Chloro-3-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 2-amino-5-chloro-3-fluoro-, methyl ester; Methyl 5-Chloro-3-Fluoro-2-aminobenzoate; 2-Amino-5-chloro-3-fluorobenzoate methyl ester; CAS 1184597-61-2
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chloro-3-Fluoro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.