Description

Methyl 2-Amino-3,5-Difluorobenzoate is a high-purity fluorinated benzoate ester derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, functionalized aromatic scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those containing difluorinated aromatic systems for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluoroaniline moiety is a critical structural feature.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers requiring fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Methyl 2-Amino-3,5-Difluorobenzoate
CAS No.	1184559-12-3
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	2-Amino-3,5-difluorobenzoic acid methyl ester; Methyl 2-amino-3,5-difluorobenzoate; Benzoic acid, 2-amino-3,5-difluoro-, methyl ester; 3,5-Difluoro-2-aminobenzoic acid methyl ester; Methyl 3,5-difluoroanthranilate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Amino-3,5-Difluorobenzoate is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA). Our quality standards are designed to meet the rigorous demands of cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.