Description

2',3,5'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity fluorinated biphenyl derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms, which are essential for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl biphenyl core contributes to bioavailability and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its ability to influence molecular alignment and electronic properties.
• Material Science Research: Employed in the synthesis of specialty polymers, ligands for catalysis, and advanced organic frameworks where fluorine substitution is desired.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-fidelity fluorinated intermediates.

Basic Information

Product Name	2',3,5'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1184513-36-7
Molecular Formula	C13H7F3O2
Molecular Weight	260.19 g/mol
Synonyms	[1,1'-Biphenyl]-4-carboxylic acid, 2',3,5'-trifluoro-; 2',3,5'-Trifluorobiphenyl-4-carboxylic acid; 4-Carboxy-2',3,5'-trifluorobiphenyl; 2,3',5'-Trifluoro-4-biphenylcarboxylic acid; 2',3,5'-Trifluoro-4-biphenylcarboxylic acid; (2',3,5'-Trifluorobiphenyl-4-yl)carboxylic acid; TFBPC Acid
EINECS	Contact for details

Quality Control

Our 2',3,5'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliable supply for sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed due to the compound's sensitivity to light and potential moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.