Description

D-Lysine-13C6 is a stable isotope-labeled analog of the essential amino acid L-lysine, where six carbon atoms are replaced with the 13C isotope. This high-purity labeled compound is critical for ensuring accuracy and reliability in quantitative mass spectrometry-based analyses. It serves as an indispensable internal standard for researchers and quality control professionals in pharmaceutical development, clinical research, and nutritional science who require precise metabolic and pharmacokinetic data.

Application

• Quantitative Mass Spectrometry (MS): Used as a stable isotope-labeled internal standard for the accurate quantification of endogenous L-lysine and related metabolites in complex biological matrices like plasma, urine, and tissue samples.
• Pharmacokinetic & Metabolic Studies: Essential for tracing amino acid uptake, turnover, and metabolism in drug development and nutritional research, enabling precise measurement of absorption and distribution.
• Clinical Diagnostics & Biomarker Research: Employed in LC-MS/MS assays to diagnose inborn errors of metabolism (e.g., hyperlysinemia) and to discover and validate disease-specific biomarkers.
• Nutritional Science & Fortification Analysis: Acts as a reference standard for quantifying lysine content and bioavailability in fortified foods, infant formula, and animal feed to ensure nutritional quality.
• Proteomics & Stable Isotope Labeling by Amino acids in Cell culture (SILAC): Facilitates accurate protein quantification and turnover studies in cell culture models for biomedical research.
• Quality Control & Method Validation: Serves as a certified reference material for validating analytical methods and ensuring compliance in pharmaceutical and food testing laboratories.

Basic Information

Product Name	D-Lysine-13C6
CAS No.	1182252-66-9
Molecular Formula	13C6H14N2O2
Molecular Weight	Contact for details
Synonyms	(2R)-2,6-Diamino-13C6-hexanoic acid; D-Lysine-13C6 (uniformly labeled); D-Lysine (U-13C6); D-Lysine-13C6, 98% CP; D-(+)-Lysine-13C6; Isotope-labeled D-Lysine; 13C6-D-Lysine; Stable Isotope Standard D-Lysine
EINECS	Contact for details

Quality Control

Our D-Lysine-13C6 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, which is paramount for trace-level quantitative analysis. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment (typically >98 atom % 13C), chemical purity (by HPLC), chiral purity, and residual solvent analysis. We adhere to relevant standards for high-purity reference materials to support your compliance needs in GLP/GMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Keep container tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to labeled structure
Isotopic Enrichment	≥98 atom % 13C
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.