Description

3-(4-Fluorophenyl)-4-Fluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block, essential for advanced organic synthesis. Its unique difluorinated biphenyl-like structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the stability imparted by fluorine atoms.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Polymer Modification: Incorporated into polymer backbones to enhance thermal stability, chemical resistance, and optical properties.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Fluorine Chemistry Reagent: Used in reactions where the introduction of a specific fluorinated aromatic moiety is required.

Basic Information

Product Name	3-(4-Fluorophenyl)-4-Fluorobenzoic Acid
CAS No.	1181452-11-8
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	4'-Fluoro-[1,1'-biphenyl]-3-carboxylic acid, 4-fluoro-3'-fluorobiphenyl-4-carboxylic acid; 3-(4-Fluorophenyl)-4-fluorobenzoic acid; 4-Fluoro-3-(4-fluorophenyl)benzoic acid; 3-Fluoro-4'-fluorobiphenyl-4-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4'-fluoro-4-fluoro-
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-4-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.