Description

Methyl 2-Amino-3-Fluoro-4-Methoxybenzoate CAS NO 1180497-48-6 is a high-purity fluorinated benzoate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of amino, fluoro, and methoxy functional groups, which enables precise molecular modifications for creating novel compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and complex heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a fluorinated aromatic core for constructing advanced electronic and photonic materials.
• Complex Ligand & Catalyst Development: The amino group allows for chelation and functionalization, useful in creating specialized catalysts for asymmetric synthesis.
• Fluorine Chemistry Research: An important substrate for studying fluorination reactions and structure-activity relationships (SAR) in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client projects.

Basic Information

Product Name	Methyl 2-Amino-3-Fluoro-4-Methoxybenzoate
CAS No.	1180497-48-6
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	2-Amino-3-fluoro-4-methoxybenzoic acid methyl ester; Methyl 2-amino-3-fluoro-4-methoxybenzoate; Benzoic acid, 2-amino-3-fluoro-4-methoxy-, methyl ester; 3-Fluoro-2-amino-4-methoxybenzoic acid methyl ester; Methyl 3-fluoro-2-amino-4-methoxybenzoate; 1180497-48-6
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-3-Fluoro-4-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.