Description

Zalcitabine Monophosphate Ammonium Salt is a key nucleotide analog intermediate with significant pharmaceutical relevance. This compound is primarily valued for its role in the synthesis of active pharmaceutical ingredients (APIs) for antiviral therapies. It is essential for research institutions and manufacturers engaged in the development and production of nucleoside-based antiviral drugs, particularly for targeting retroviruses.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: Critical precursor in the synthesis of Zalcitabine and related nucleoside analog drugs.
• Antiviral Drug Research & Development: Used as a building block in medicinal chemistry for creating new therapeutic candidates against viral infections.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies and metabolic pathway investigations.
• Pharmaceutical Manufacturing: Employed in scaled-up GMP production processes for finished dosage forms.
• Reference Standard: Utilized as a high-purity certified reference material (CRM) for quality control and analytical method development.

Basic Information

Item	Detail
Product Name	Zalcitabine Monophosphate Ammonium Salt
CAS No.	1179343-05-5
Molecular Formula	C9H16N4O7P
Molecular Weight	323.22 g/mol
Synonyms	2',3'-Dideoxycytidine monophosphate ammonium salt; ddCMP ammonium salt; Zalcitabine 5'-monophosphate ammonium salt; 4-Amino-1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2(1H)-pyrimidinone 5'-(dihydrogen phosphate) ammonium salt; Ammonium zalcitabine monophosphate
EINECS	Contact for details

Quality Control

Our Zalcitabine Monophosphate Ammonium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) are provided, detailing compliance with in-house specifications developed for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.5 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.