Description

3,3',4'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is a high-purity fluorinated biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the precise trifluoro substitution pattern, which imparts unique electronic and steric properties essential for modulating the activity of target molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly in the creation of complex small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used as a core scaffold in the development of next-generation herbicides, fungicides, and insecticides, leveraging fluorine's effects on bioavailability and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated liquid crystal compounds and electron-transport/hole-blocking materials in organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced thermal stability, chemical resistance, and specific optical properties.
• Chemical Synthesis: Utilized as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Stille) and for introducing the biphenyl-4-carboxylic acid moiety into complex molecular architectures.
• Material Science Research: Employed in the development of advanced organic semiconductors and non-linear optical (NLO) materials.

Basic Information

Product Name	3,3',4'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid
CAS No.	1179174-66-3
Molecular Formula	C13H7F3O2
Molecular Weight	260.19 g/mol
Synonyms	4'-Carboxy-3,3',4-trifluorobiphenyl; [1,1'-Biphenyl]-4-carboxylic acid, 3,3',4'-trifluoro-; 3,3',4'-Trifluorobiphenyl-4-carboxylic Acid; 4-(3,4-Difluorophenyl)-2-fluorobenzoic Acid; 3,3',4'-Trifluoro-4-biphenylcarboxylic Acid; 3,4,3'-Trifluorobiphenyl-4'-carboxylic Acid; TFBPC Acid
EINECS	Contact for details

Quality Control

Our 3,3',4'-Trifluoro-[1,1'-Biphenyl]-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if necessary and opened with minimal exposure to ambient humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.