Description

5-(3-Fluorophenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block, essential for advanced organic synthesis. This compound is valued for its role in introducing specific fluorinated biphenyl motifs, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and receptor modulator programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorinated aromatic structure enhances stability and bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving performance characteristics.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex fluorinated biaryl systems.
• Chemical Research: Utilized in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	5-(3-Fluorophenyl)-2-Fluorobenzoic Acid
CAS No.	1178958-75-2
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	2-Fluoro-5-(3-fluorophenyl)benzoic Acid; 5-(3-Fluorophenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-2-carboxylic acid, 3-fluoro-5'-fluoro-; 3-Fluoro-5'-fluoro[1,1'-biphenyl]-2-carboxylic Acid; 2'-Fluoro-5-(3-fluorophenyl)benzoic Acid; 3-Fluoro-5-(3-fluorophenyl)benzoic Acid (isomer check); F2-Ph-COOH (common abbreviation)
EINECS	Contact for details

Quality Control

Our 5-(3-Fluorophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area Percent)
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.