Description

Methyl 3-Amino-2,4-Dichloro-5-Fluorobenzoate is a high-purity fluorinated benzoate derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its multifunctional halogenated and aminated aromatic structure, enabling precise chemical transformations for complex molecule construction. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to build active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drugs with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom and chlorine substituents contribute to biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Methyl 3-Amino-2,4-Dichloro-5-Fluorobenzoate
CAS No.	1159908-24-3
Molecular Formula	C8H6Cl2FNO2
Molecular Weight	238.04 g/mol
Synonyms	Methyl 3-amino-2,4-dichloro-5-fluorobenzoate; 2,4-Dichloro-5-fluoro-3-aminobenzoic acid methyl ester; 3-Amino-2,4-dichloro-5-fluorobenzoic acid methyl ester; Benzoic acid, 3-amino-2,4-dichloro-5-fluoro-, methyl ester; Methyl 3-amino-2,4-dichloro-5-fluorobenzenecarboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-2,4-Dichloro-5-Fluorobenzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment, ensuring full traceability and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.