Description

5-(2-Fluorophenyl)Picolinic Acid is a high-purity, specialized organic building block featuring a picolinic acid core substituted with a fluorinated phenyl ring. This compound matters as a critical intermediate in modern pharmaceutical and agrochemical research, where its unique structure enables the synthesis of novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorophenyl moiety.
• Ligand for Catalysis: Serves as a precursor for chelating ligands in transition metal catalysis, useful in cross-coupling and other synthetic transformations.
• Material Science Research: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, functionalized structure.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity fluorinated intermediates.

Basic Information

Product Name	5-(2-Fluorophenyl)Picolinic Acid
CAS No.	1158763-56-4
Molecular Formula	C₁₂H₈FNO₂
Molecular Weight	217.20 g/mol
Synonyms	2-Fluoro-5-(pyridine-2-carbonyl)benzene; 2-Pyridinecarboxylic acid, 5-(2-fluorophenyl)-; 5-(2-Fluorophenyl)-2-pyridinecarboxylic acid; 5-(o-Fluorophenyl)picolinic acid; 5-(2-Fluorophenyl)-2-carboxypyridine; 2-Fluoro-5-(2-pyridylcarbonyl)benzene; 5-(2-Fluorophenyl)pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.