Description

Ethyl 2-Bromo-4-Fluoro-5-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block designed for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated nitroaromatic structure.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Employed in the creation of labeled compounds or molecular probes for biochemical and diagnostic research applications.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) for constructing complex biaryl systems.
• Nucleophilic Aromatic Substitution: The nitro and halogen groups make it a suitable electrophile for displacement reactions to introduce diverse functionalities.

Basic Information

Product Name	Ethyl 2-Bromo-4-Fluoro-5-Nitrobenzoate
CAS No.	1153284-99-1
Molecular Formula	C9H7BrFNO4
Molecular Weight	292.06 g/mol
Synonyms	2-Bromo-4-fluoro-5-nitrobenzoic acid ethyl ester; Benzoic acid, 2-bromo-4-fluoro-5-nitro-, ethyl ester; Ethyl 2-bromo-4-fluoro-5-nitrobenzoate; Ethyl α-bromo-4-fluoro-5-nitrobenzoate; 5-Nitro-2-bromo-4-fluorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-4-Fluoro-5-Nitrobenzoate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.