Description

5-Chloro-2-Fluoro-3-Nitro-Benzoic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitro functional groups.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex dyes and organic pigments due to its nitro-substituted benzoic acid structure.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in synthetic organic chemistry and methodology development.

Basic Information

Product Name	5-Chloro-2-Fluoro-3-Nitro-Benzoic Acid
CAS No.	1153279-85-6
Molecular Formula	C7H3ClFNO4
Molecular Weight	219.55 g/mol
Synonyms	3-Nitro-5-chloro-2-fluorobenzoic acid; Benzoic acid, 5-chloro-2-fluoro-3-nitro-; 5-Chloro-2-fluoro-3-nitrobenzoic acid; 2-Fluoro-5-chloro-3-nitrobenzoic acid; 5-Chloro-2-fluoranyl-3-nitro-benzoic acid; 1153279-85-6; 5-Chloro-2-fluoro-3-nitro-benzoic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-3-Nitro-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere for long-term stability and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.