Description

2-(S)-(3,5-Bis(4-(Trifluoromethyl)Phenyl)Phenyl)-4-Methylpentanoic Acid CAS NO 1146594-87-7 is a high-value, optically active chiral intermediate featuring a complex polyaromatic structure with multiple trifluoromethyl groups. This compound is engineered to serve as a critical building block in advanced pharmaceutical and agrochemical synthesis, where its specific stereochemistry and fluorine content are essential for bioactivity and metabolic stability. It is primarily required by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Agrochemical Active Ingredient Synthesis: Serves as a sophisticated building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Utilized in the research and preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Investigated for its potential in creating advanced organic electronic materials due to its conjugated aromatic system and fluorine substituents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	2-(S)-(3,5-Bis(4-(Trifluoromethyl)Phenyl)Phenyl)-4-Methylpentanoic Acid
CAS No.	1146594-87-7
Molecular Formula	C32H24F6O2
Molecular Weight	554.52 g/mol
Synonyms	(S)-2-(3,5-Bis(4-(trifluoromethyl)phenyl)phenyl)-4-methylpentanoic acid; 2-(S)-(3,5-Bis(4-(Trifluoromethyl)Phenyl)Phenyl)-4-Methylpentanoic Acid; 1146594-87-7; 2-(3,5-Bis[4-(trifluoromethyl)phenyl]phenyl)-4-methyl-(S)-pentanoic acid; (S)-4-Methyl-2-[3,5-bis[4-(trifluoromethyl)phenyl]phenyl]pentanoic acid
EINECS	Contact for details

Quality Control

Our production of 2-(S)-(3,5-Bis(4-(Trifluoromethyl)Phenyl)Phenyl)-4-Methylpentanoic Acid adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and commercial projects with consistent quality, traceable from raw materials to final product.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizers, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.