Description

2-Bromo-5-(4-Fluoro-Phenyl)-Thiazole-4-Carboxylic Acid is a high-value heterocyclic building block essential for advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of new active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and fluorophenyl moieties.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and liquid crystals with specific electronic or optical properties.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research to study protein interactions and enzyme mechanisms.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-5-(4-Fluoro-Phenyl)-Thiazole-4-Carboxylic Acid
CAS No.	1137129-05-5
Molecular Formula	C10H5BrFNO2S
Molecular Weight	302.12 g/mol
Synonyms	2-Bromo-5-(4-fluorophenyl)-1,3-thiazole-4-carboxylic acid; 4-Carboxy-2-bromo-5-(4'-fluorophenyl)thiazole; 5-(4-Fluorophenyl)-2-bromothiazole-4-carboxylic acid; 1137129-05-5; 2-Bromo-5-(p-fluorophenyl)-4-thiazolecarboxylic acid; 2-Bromo-5-(4-fluorophenyl)-4-thiazolecarboxylic acid; 2-Bromo-5-(4-fluorophenyl)thiazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(4-Fluoro-Phenyl)-Thiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.