Description

3-(3,4-Difluorophenyl)-1-Methyl-1{H}-Pyrazole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its difluorophenyl and pyrazole carboxylic acid structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of small molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, leveraging the bioactivity of the pyrazole core.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of specialized ligands or functional materials requiring fluorinated aromatic systems.

Basic Information

Product Name	3-(3,4-Difluorophenyl)-1-Methyl-1{H}-Pyrazole-5-Carboxylic Acid
CAS No.	1134692-74-2
Molecular Formula	C11H8F2N2O2
Molecular Weight	238.19 g/mol
Synonyms	1-Methyl-3-(3,4-difluorophenyl)-1H-pyrazole-5-carboxylic acid; 3-(3,4-Difluorophenyl)-1-methyl-1H-pyrazole-5-carboxylic acid; 1H-Pyrazole-5-carboxylic acid, 3-(3,4-difluorophenyl)-1-methyl-; 1134692-74-2; 3-(3,4-Difluorophenyl)-1-methylpyrazole-5-carboxylic acid; 5-Carboxy-1-methyl-3-(3,4-difluorophenyl)pyrazole
EINECS	Contact for details

Quality Control

Our 3-(3,4-Difluorophenyl)-1-Methyl-1{H}-Pyrazole-5-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.