Description

Methyl 5-Bromo-2-Methoxy-4-(Trifluoromethyl)Benzoate CAS NO 1131587-97-7 is a high-purity, multi-functional benzoate ester derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic combination of bromo, methoxy, and trifluoromethyl functional groups, which enables precise molecular modifications for developing novel compounds with enhanced properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients and fine chemicals requiring specific electronic and steric characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of molecules with trifluoromethyl groups for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, where the bromine atom allows for further functionalization to optimize biological activity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as liquid crystals or charge-transport materials, leveraging its aromatic core and substituents.
• Cross-Coupling Reactions: The bromoaryl moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, facilitating complex molecule assembly.
• Fluorine Chemistry: A valuable reagent for introducing the trifluoromethyl group into target molecules, a common strategy in medicinal chemistry to modulate lipophilicity and potency.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and proprietary research chemicals.

Basic Information

Product Name	Methyl 5-Bromo-2-Methoxy-4-(Trifluoromethyl)Benzoate
CAS No.	1131587-97-7
Molecular Formula	C10H8BrF3O3
Molecular Weight	313.07 g/mol
Synonyms	5-Bromo-2-methoxy-4-(trifluoromethyl)benzoic acid methyl ester; Methyl 5-bromo-2-methoxy-4-(trifluoromethyl)benzoate; Benzoic acid, 5-bromo-2-methoxy-4-(trifluoromethyl)-, methyl ester; 5-Bromo-2-methoxy-alpha,alpha,α-trifluoro-p-toluic acid methyl ester; Methyl 5-bromo-2-methoxy-4-trifluoromethylbenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Bromo-2-Methoxy-4-(Trifluoromethyl)Benzoate adheres to a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry. We provide full traceability and Certificates of Analysis (COA) upon request, detailing all critical parameters to ensure the material meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.