Description

2-Fluoro-4-Piperazinobenzoic Acid is a high-value pharmaceutical intermediate and versatile organic building block. Its molecular structure, featuring both a piperazine ring and a benzoic acid core with a fluorine substituent, makes it a critical precursor in modern medicinal chemistry. This compound is essential for research and development chemists, particularly in the pharmaceutical and agrochemical sectors, who require high-purity, structurally complex intermediates for synthesizing novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in the design and development of new drug candidates, leveraging the piperazine moiety for receptor binding and the fluorine atom for metabolic stability.
• Agrochemical Synthesis: Serves as a precursor for developing advanced herbicides and fungicides, where the fluorine group enhances biological activity.
• Chemical Biology Probes: Utilized in the creation of labeled compounds and probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated aromatic compounds with nitrogen heterocycles.

Basic Information

Product Name	2-Fluoro-4-Piperazinobenzoic Acid
CAS No.	1121613-69-1
Molecular Formula	C11H13FN2O2
Molecular Weight	224.23 g/mol
Synonyms	4-(Piperazin-1-yl)-2-fluorobenzoic Acid; 2-Fluoro-4-(1-piperazinyl)benzoic Acid; Benzoic acid, 2-fluoro-4-(1-piperazinyl)-; 2-Fluoro-4-piperazin-1-yl-benzoic acid; 2-Fluoro-4-(piperazin-1-yl)benzoic Acid; 1121613-69-1; 2-Fluoro-4-piperazinobenzoic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Piperazinobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.