Description

Methyl 3-Iodo-4-Fluorobenzoate is a high-purity fluorinated and iodinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated and iodinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and iodine atoms enhance biological activity and stability.
• Liquid Crystal Materials (LCM): Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the creation of electron-transport or host materials for organic electronic devices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive iodo group.
• Chemical Research & Development: A versatile building block for exploring new chemical spaces in medicinal and materials chemistry.

Basic Information

Product Name	Methyl 3-Iodo-4-Fluorobenzoate
CAS No.	1121586-29-5
Molecular Formula	C8H6FIO2
Molecular Weight	280.04 g/mol
Synonyms	3-Iodo-4-fluorobenzoic acid methyl ester; Methyl 3-iodo-4-fluorobenzoate; Benzoic acid, 3-iodo-4-fluoro-, methyl ester; 4-Fluoro-3-iodobenzoic acid methyl ester; Methyl 4-fluoro-3-iodobenzoate; 1121586-29-5; MFCD30533333
EINECS	Contact for details

Quality Control

Our Methyl 3-Iodo-4-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.