Description

2-(5-Bromo-2-Fluoro-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex organic frameworks. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Research: An indispensable reagent in academic and industrial R&D labs for palladium-catalyzed cross-coupling reactions.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Custom Synthesis: Provides a versatile handle for the late-stage functionalization and diversification of complex molecules.

Basic Information

Product Name	2-(5-Bromo-2-Fluoro-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1111096-03-7
Molecular Formula	C13H17BBrFO2
Molecular Weight	315.99 g/mol
Synonyms	5-Bromo-2-fluoro-4-methylbenzeneboronic acid pinacol ester; (5-Bromo-2-fluoro-4-methylphenyl)boronic acid pinacol ester; 2-Fluoro-5-bromo-4-methylbenzeneboronic acid pinacol ester; Pinacol (5-bromo-2-fluoro-4-methylphenyl)boronate; 5-Bromo-2-fluoro-p-tolylboronic acid pinacol ester; CAS 1111096-03-7
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2-Fluoro-4-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.