Description

Neu5Acα(2-6) n-Glycan 2Ab (500Pmol/Vial) is a defined, high-purity sialylated N-glycan standard, critical for analytical method development and calibration in glycobiology research. This compound serves as an essential reference material for the precise characterization of glycan structures, enabling accurate quantification and structural elucidation in complex biological samples. It is primarily utilized by researchers and quality control laboratories in the biopharmaceutical, diagnostic, and life science sectors to ensure the consistency and efficacy of glycoprotein-based therapeutics, including monoclonal antibodies and vaccines.

Application

• Glycoprotein Therapeutic Analysis: As a critical standard for characterizing the sialylation profile of monoclonal antibodies, fusion proteins, and other biologics to ensure batch consistency and optimize efficacy.
• Diagnostic Assay Development: For calibrating and validating diagnostic platforms, such as lectin arrays or mass spectrometry-based assays, that detect disease-specific glycan biomarkers.
• Glycosylation Pathway Research: Used in enzymatic studies to investigate the activity and specificity of sialyltransferases and other glycosyltransferases.
• Mass Spectrometry Calibration: Provides a known mass and fragmentation pattern for instrument calibration and method development in LC-MS and MALDI-TOF workflows.
• Quality Control Reference Standard: Essential for in-house QC testing of glycan release and labeling kits, and for verifying the performance of analytical columns (e.g., HILIC, PGC).
• Vaccine Development: Supports the analysis of glycosylation on viral envelope proteins or recombinant vaccine antigens, which can impact immunogenicity.

Basic Information

Product Name	Neu5Acα(2-6) n-Glycan 2Ab (500Pmol/Vial)
CAS No.	1107646-22-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Aminobenzamide-labeled N-Glycan with α2-6 linked N-Acetylneuraminic acid; Sialylated N-Glycan 2AB derivative; N-Acetylneuraminic acid α-(2→6)-linked N-Glycan-2AB; Glycan Standard 2AB; Sia-α2-6-Gal-β1-4-GlcNAc-...-2AB; Fluorescently labeled N-Glycan; 2AB-N-Glycan standard
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Neu5Acα(2-6) n-Glycan 2Ab is characterized using advanced analytical techniques, including HPLC and mass spectrometry, to confirm identity, purity, and precise molar quantification. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality system supports research and development under cGMP-like controls where applicable.

Storage

Preserve in the original sealed vial within a tightly closed secondary container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation. For long-term stability, store under inert atmosphere after initial use.

Specification

Item	Specification
Appearance	White to off-white solid / film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Quantification)	500 ± 25 Pmol/Vial
Water Content (KF)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.