Description

(6-(2-Fluorophenoxy)Pyridin-3-Yl)Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its primary commercial value lies in its role as a versatile building block for constructing complex molecules via cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials. Its specific structure makes it a critical reagent for introducing the (6-(2-fluorophenoxy)pyridin-3-yl) moiety into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorophenoxy and pyridine motifs for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of advanced organic polymers and functional materials.
• Suzuki-Miyaura Cross-Coupling: The premier application, enabling the formation of carbon-carbon bonds between its boronic acid group and various organic halides under palladium catalysis.
• Ligand Synthesis: Used to create novel bidentate or tridentate ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Item	Detail
Product Name	(6-(2-Fluorophenoxy)Pyridin-3-Yl)Boronic Acid
CAS No.	1105663-76-0
Molecular Formula	C11H9BFNO3
Molecular Weight	233.01 g/mol
Synonyms	2-Fluoro-6-(5-borono-2-pyridyloxy)benzene; (6-(2-Fluorophenoxy)-3-pyridinyl)boronic acid; 5-(2-Fluorophenoxy)pyridine-3-boronic acid; 3-Borono-5-(2-fluorophenoxy)pyridine; 2-Fluorophenyl 5-boronopyridin-3-yl ether; Boronic acid, B-[6-[(2-fluorophenyl)oxy]-3-pyridinyl]-
EINECS	Contact for details

Quality Control

Every batch of (6-(2-Fluorophenoxy)Pyridin-3-Yl)Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.