Description

Lersivirine (CAS NO 1100749-38-9) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for antiviral research and therapeutic applications. This compound is of significant interest for its targeted mechanism of action against specific viral strains, offering a pathway for advanced pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel antiviral agents.

Application

• Antiviral Drug Research: A key intermediate or active pharmaceutical ingredient (API) in the development of next-generation HIV therapeutics.
• Biochemical Assays: Used as a reference standard or pharmacological tool in virology and enzymology studies to understand viral replication mechanisms.
• Pharmaceutical Synthesis: Serves as a critical building block in the multi-step synthesis of complex antiviral drug candidates under Good Manufacturing Practice (GMP) conditions.
• Preclinical Development: Employed in in vitro and in vivo studies to evaluate efficacy, pharmacokinetics, and toxicity profiles.

Basic Information

Product Name	Lersivirine
CAS No.	1100749-38-9
Molecular Formula	C₁₇H₁₉ClN₆O
Molecular Weight	358.82 g/mol
Synonyms	UK-453,061; Lersivirine (UK-453061); 5-[(3,5-Dichloro-4-pyridinyl)oxy]-4-ethoxy-1-[(1-methylethyl)sulfonyl]-1H-indole-2-carbonitrile; UK453061; UK 453061; Lersivirine [USAN]; 1H-Indole-2-carbonitrile, 5-[(3,5-dichloro-4-pyridinyl)oxy]-4-ethoxy-1-[(1-methylethyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our Lersivirine is manufactured and tested to meet high-purity standards suitable for research and development. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) is provided, detailing all specifications and results to ensure traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.