Description

5-(2,6-Difluorophenyl)Thiophene-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block featuring a thiophene core flanked by a carboxylic acid group and a difluorinated phenyl ring. This compound is critical for research and development in advanced organic synthesis, where its unique structure enables the creation of novel molecular architectures. It is primarily sought after by pharmaceutical and agrochemical R&D teams for use as a key intermediate in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Serves as a versatile building block for creating novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and fluorinated arene motifs.
• Material Science Research: Used in the development of advanced organic electronic materials, such as semiconductors and conductive polymers, due to the electron-rich thiophene system.
• Chemical Biology Probes: Employed as a core structure for designing fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Details
Product Name	5-(2,6-Difluorophenyl)Thiophene-2-Carboxylic Acid
CAS No.	1094440-66-0
Molecular Formula	C11H6F2O2S
Molecular Weight	240.23 g/mol
Synonyms	2,6-Difluoro-5-(thiophen-2-yl)benzoic Acid; 5-(2,6-Difluorophenyl)-2-thiophenecarboxylic Acid; 2-Thiophenecarboxylic acid, 5-(2,6-difluorophenyl)-; 1094440-66-0; AKOS025146065; 5-(2,6-Difluorophenyl)thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(2,6-Difluorophenyl)Thiophene-2-Carboxylic Acid is produced and tested under a strict quality management system. We ensure compliance with rigorous internal specifications designed for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.