Description

5-Fluoro-2-(Trifluoromethoxy)Cinnamic Acid is a high-purity fluorinated cinnamic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular architecture, which combines a cinnamic acid backbone with strategically placed fluorine and trifluoromethoxy groups, enabling precise modifications to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atoms can improve metabolic stability and bioavailability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Liquid Crystal & OLED Development: The rigid, fluorinated structure makes it valuable for synthesizing components for display technologies and organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Synthesis: Utilized to create tagged or modified molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for use in client-specific research and scale-up projects.

Basic Information

Product Name	5-Fluoro-2-(Trifluoromethoxy)Cinnamic Acid
CAS No.	1092460-94-0
Molecular Formula	C₁₀H₆F₄O₃
Molecular Weight	250.15 g/mol
Synonyms	(E)-3-[5-Fluoro-2-(trifluoromethoxy)phenyl]acrylic acid; 5-Fluoro-2-(trifluoromethoxy)cinnamic acid; 2-(Trifluoromethoxy)-5-fluorocinnamic acid; (E)-3-(5-Fluoro-2-(trifluoromethoxy)phenyl)-2-propenoic acid; 5-Fluoro-α,2-bis(trifluoromethyl)benzeneacrylic acid (related); FTCA (abbreviation); 1092460-94-0
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Trifluoromethoxy)Cinnamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. For projects requiring specific regulatory support, we can discuss compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its nature as a strong acid/organic solvent, ensure containers are properly sealed and stored on secondary containment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.