Description

3-Fluoro-5-Oxo-5,6,7,8-Tetrahydronaphthalene-2-Carboxylic Acid is a high-value fluorinated naphthalene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid and a ketone functional group on a fluorinated tetrahydronaphthalene scaffold, makes it indispensable for constructing complex molecular architectures. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced organic materials with specific electronic properties.
• Chemical Research: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Valuable substrate for exploring novel fluorination reactions and synthesizing other complex fluorinated aromatic compounds.

Basic Information

Product Name	3-Fluoro-5-Oxo-5,6,7,8-Tetrahydronaphthalene-2-Carboxylic Acid
CAS No.	1092348-21-4
Molecular Formula	C11H9FO3
Molecular Weight	208.19 g/mol
Synonyms	2-Carboxy-3-fluoro-5-oxo-5,6,7,8-tetrahydronaphthalene; 3-Fluoro-5-oxo-5,8-dihydro-2-naphthoic acid; 3-Fluoro-5-oxo-5,6,7,8-tetrahydro-2-naphthalenecarboxylic acid; 5,6,7,8-Tetrahydro-3-fluoro-5-oxo-2-naphthoic acid; 1092348-21-4; 3-Fluoro-5-oxotetralin-2-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-5-Oxo-5,6,7,8-Tetrahydronaphthalene-2-Carboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets exacting specifications for use in GMP environments. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results from HPLC, NMR, and other relevant tests.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.