Description

5-Fluoro-3-Phenylbenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its unique substitution pattern can modulate biological activity and physicochemical properties. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic cores in electronic and display materials.
• Organic Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.
• Academic & Industrial R&D: Used in exploratory chemistry for method development and creating libraries of fluorinated compounds.

Basic Information

Product Name	5-Fluoro-3-Phenylbenzoic Acid
CAS No.	1082565-35-2
Molecular Formula	C13H9FO2
Molecular Weight	216.21 g/mol
Synonyms	3-Phenyl-5-fluorobenzoic Acid; 5-Fluoro-[1,1'-biphenyl]-3-carboxylic Acid; 5-Fluoro-3-biphenylcarboxylic Acid; 3'-Fluoro-[1,1'-biphenyl]-3-carboxylic Acid; 3-(5-Fluorophenyl)benzoic Acid; 5-Fluoro-3-phenylbenzoic acid; [1,1'-Biphenyl]-3-carboxylic acid, 5'-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Phenylbenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.