Description

2-Bromo-4-Chloro-6-Fluorobenzoic Acid is a high-purity, multi-halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the halogen atoms contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its electron-withdrawing halogen groups.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-4-Chloro-6-Fluorobenzoic Acid
CAS No.	1082040-61-6
Molecular Formula	C7H3BrClFO2
Molecular Weight	253.45 g/mol
Synonyms	Benzoic acid, 2-bromo-4-chloro-6-fluoro-; 4-Chloro-2-bromo-6-fluorobenzoic acid; 6-Fluoro-2-bromo-4-chlorobenzoic acid; 2-Bromo-4-chloro-6-fluoro-benzoic acid; BCFBA (abbreviation); 1082040-61-6; 2-Br-4-Cl-6-F-Benzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Chloro-6-Fluorobenzoic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our standard grade typically meets a purity specification of ≥97% (HPLC), with custom purifications up to ≥99% available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.