Description

Agomelatine-D6 CAS NO 1079389-42-6 is a deuterium-labeled analog of the antidepressant drug agomelatine, serving as a critical internal standard for precise analytical quantification. This high-purity stable isotope-labeled compound is essential for ensuring accuracy and reliability in pharmacokinetic and metabolic studies. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in bioanalytical method development and validation.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a quantitative reference standard in bioanalytical assays for agomelatine in biological matrices like plasma and serum.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Facilitates accurate tracking and measurement of the parent drug and its metabolites in absorption, distribution, metabolism, and excretion (ADME) research.
• Clinical Trial Support: Enables precise drug level monitoring in patient samples during clinical development phases.
• Forensic and Anti-Doping Analysis: Supports high-confidence identification and quantification of agomelatine in specialized forensic toxicology or sports doping control.
• Pharmaceutical Quality Control: Can be employed in method development for impurity profiling and stability testing of drug substances and products.
• Academic and Industrial Research: Serves as a key reagent in neuroscience and psychiatric disorder research involving melatonin receptor agonists.

Basic Information

Product Name	Agomelatine-D6
CAS No.	1079389-42-6
Molecular Formula	C15H17D6NO2
Molecular Weight	255.38 g/mol
Synonyms	N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide-d6; S 20098-d6; S20098-d6; Valdoxan-d6; Thymanax-d6; Melitor-d6; Deuterated Agomelatine; Agomelatine (hexadeuterated)
EINECS	Contact for details

Quality Control

Our Agomelatine-D6 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity by HPLC, and confirmation of structure. We adhere to relevant industry standards for reference materials, and custom purity grades or packaging are available to meet specific research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccants and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (Mass Spectrometry)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Enrichment (D-content)	≥99.0 atom % D
Chemical Purity (by HPLC)	≥95.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.