Description

2,5-Dichloro-3-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced material development. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific chlorinated pyridine motifs.
• Material Science & OLED Development: Employed as a monomer or building block for creating electron-transport materials, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to introduce the 3-pyridyl boronate functionality into more complex molecular architectures.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Ligand Synthesis: Useful for the preparation of novel bidentate or polydentate ligands for catalysis and coordination chemistry.

Basic Information

Product Name	2,5-Dichloro-3-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine
CAS No.	1073371-98-8
Molecular Formula	C11H14BCl2NO2
Molecular Weight	274.95 g/mol
Synonyms	2,5-Dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dichloropyridine; 2,5-Dichloro-3-pyridineboronic acid pinacol ester; (2,5-Dichloropyridin-3-yl)boronic acid pinacol ester; 2,5-Dichloro-3-pyridinylboronic acid pinacol ester; 1073371-98-8; 2,5-Dichloro-3-(pinacolatoboryl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dichloro-3-(4,4,5,5-Tetramethyl-[1,3,2]-Dioxaborolan-2-Yl)Pyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications and pharmaceutical research. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.