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Benzeneacetic Acid, α-Hydroxy-, (αr)-, Compd. With (αr)-α-Methyl-1-Naphthalenemethanamine (1:1) CAS NO 1073144-62-3
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CAS No.:1073144-62-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Benzeneacetic Acid, α-Hydroxy-, (αr)-, Compd. With (αr)-α-Methyl-1-Naphthalenemethanamine (1:1) is a high-purity, non-racemic salt complex of mandelic acid and (R)-1-(1-naphthyl)ethylamine, serving as a critical chiral intermediate or resolving agent in advanced organic synthesis. This compound matters for its ability to impart or control stereochemistry, a fundamental requirement for developing active pharmaceutical ingredients (APIs) and other high-value enantiomerically pure substances. Industries requiring precise chiral control, such as pharmaceutical R&D, fine chemical manufacturing, and advanced material science, are the primary users of this specialized chemical.
Application
- Chiral Resolution Agent: Used for the separation of racemic mixtures of carboxylic acids or other acidic compounds via diastereomeric salt formation.
- Pharmaceutical Intermediate: Serves as a key building block or chiral auxiliary in the synthesis of enantiomerically pure drugs and active pharmaceutical ingredients (APIs).
- Asymmetric Synthesis Catalyst/Additive: Employed to induce chirality in catalytic reactions or as a ligand precursor in metal-catalyzed transformations.
- Fine Chemical Synthesis: Utilized in the research and production of specialty chemicals, agrochemicals, and flavors & fragrances where specific stereochemistry is required.
- Analytical Standard: Acts as a reference standard for method development and quality control in chiral HPLC or other analytical techniques.
- Academic & Industrial Research: A valuable tool for chemists in universities and corporate labs exploring new synthetic methodologies and chiral compounds.
Basic Information
| Product Name | Benzeneacetic Acid, α-Hydroxy-, (αr)-, Compd. With (αr)-α-Methyl-1-Naphthalenemethanamine (1:1) |
| CAS No. | 1073144-62-3 |
| Molecular Formula | C20H21NO3 |
| Molecular Weight | 323.39 g/mol |
| Synonyms | (R)-Mandelic Acid (R)-1-(1-Naphthyl)ethylamine Salt (1:1); (R)-Mandelic Acid - (R)-1-(1-Naphthyl)ethylamine Complex; (R)-1-Phenylethanol-α-carboxylic Acid Compound with (R)-1-(1-Naphthyl)ethylamine; (R,R)-Mandelic Acid-1-(1-Naphthyl)ethylamine Salt; Mandelic Acid-(R)-1-(1-Naphthyl)ethylamine Salt; Chiral Mandelic Acid Amine Salt; α-Hydroxybenzeneacetic Acid Compound with (R)-α-Methyl-1-naphthalenemethanamine |
| EINECS | Contact for details |
Quality Control
Our Benzeneacetic Acid, α-Hydroxy-, (αr)-, Compd. With (αr)-α-Methyl-1-Naphthalenemethanamine (1:1) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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