Description

2-Bromo-3-Butoxy-6-Fluorophenylboronic Acid is a specialized organoboron compound, specifically a fluorinated and brominated phenylboronic acid derivative. This chemical matters as a high-value building block in modern synthetic chemistry, enabling the precise construction of complex molecules through cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific halogenated and fluorinated aromatic structures.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where fluorine and bromine substitution tunes electronic properties.
• Chemical Biology Probes: Utilized to create boronic acid-based probes and sensors for detecting biological analytes like sugars or peroxides.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Bromo-3-Butoxy-6-Fluorophenylboronic Acid
CAS No.	1072951-95-1
Molecular Formula	C₁₀H₁₃BBrFO₃
Molecular Weight	291.93 g/mol
Synonyms	(2-Bromo-3-butoxy-6-fluorophenyl)boronic acid; 2-Bromo-3-butoxy-6-fluorobenzeneboronic acid; B-(2-Bromo-3-butoxy-6-fluorophenyl)boronic acid; 1072951-95-1; AKOS025310999; FT-0777687; BRN 29329570
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Butoxy-6-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container must be kept tightly sealed and allowed to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.