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6-Bromo-3-Butoxy-2-Fluorophenylboronic Acid CAS NO 1072951-88-2
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CAS No.:1072951-88-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Bromo-3-Butoxy-2-Fluorophenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the construction of complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery and specialty chemical production.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex fluorinated and brominated aromatic systems.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogen and fluorine substituents for bioactivity.
- Material Science Research: Employed in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials, where its structure aids in tuning electronic properties.
- Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
- Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and diagnostics.
- Custom Synthesis and Contract Manufacturing: Supplied to CROs (Contract Research Organizations) and CMOs (Contract Manufacturing Organizations) for bespoke synthesis projects requiring high-fidelity boronic acid reagents.
Basic Information
| Product Name | 6-Bromo-3-Butoxy-2-Fluorophenylboronic Acid |
| CAS No. | 1072951-88-2 |
| Molecular Formula | C₁₀H₁₃BBrFO₃ |
| Molecular Weight | 290.93 g/mol |
| Synonyms | 2-Fluoro-6-bromo-3-butoxybenzeneboronic acid; (6-Bromo-3-butoxy-2-fluorophenyl)boronic acid; B-(6-Bromo-3-butoxy-2-fluorophenyl)boronic acid; 6-Bromo-3-butoxy-2-fluorobenzeneboronic acid; 2-Fluoro-6-bromo-3-n-butoxybenzeneboronic acid; 1072951-88-2; AKOS025310647 |
| EINECS | Contact for details |
Quality Control
Every batch of 6-Bromo-3-Butoxy-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥97.0% (Area %) |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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