Description

6-Bromo-2-Fluoro-3-Propoxyphenylboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific halogenated and fluorinated aromatic frameworks.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular architecture is crucial.
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic acid derivatives.

Basic Information

Product Name	6-Bromo-2-Fluoro-3-Propoxyphenylboronic Acid
CAS No.	1072951-85-9
Molecular Formula	C9H11BBrFO3
Molecular Weight	276.90 g/mol
Synonyms	(6-Bromo-2-fluoro-3-propoxyphenyl)boronic acid; 2-Fluoro-6-bromo-3-propoxybenzeneboronic acid; 3-Bromo-6-fluoro-2-propoxybenzeneboronic acid; Boronic acid, B-(6-bromo-2-fluoro-3-propoxyphenyl)-; 1072951-85-9; 6-Bromo-2-fluoro-3-propoxybenzeneboronic acid; 6-Bromo-2-fluoro-3-propoxy phenylboronic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Fluoro-3-Propoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.