Description

2-Bromo-6-Fluoro-3-Isopropoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the halogen and alkoxy substituents for bioactivity modulation.
• Material Science Research: Employed in the creation of organic electronic materials and liquid crystals, where the boronic acid group facilitates polymerization and molecular assembly.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex fragments in multi-step synthesis projects.

Basic Information

Product Name	2-Bromo-6-Fluoro-3-Isopropoxyphenylboronic Acid
CAS No.	1072951-75-7
Molecular Formula	C9H11BBrFO3
Molecular Weight	275.90 g/mol
Synonyms	(2-Bromo-6-fluoro-3-isopropoxyphenyl)boronic acid; 2-Bromo-6-fluoro-3-(propan-2-yloxy)benzeneboronic acid; 2-Bromo-6-fluoro-3-isopropoxybenzeneboronic acid; Boronic acid, B-(2-bromo-6-fluoro-3-isopropoxyphenyl)-; 1072951-75-7; AKOS025310947; BRN 29345075
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-6-Fluoro-3-Isopropoxyphenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening containers to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.