Description

2-[(3'-(Trifluoromethyl)Phenoxy)Methyl]Phenylboronic Acid is a specialized organoboron compound featuring a trifluoromethylphenoxy moiety, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in the synthesis of complex molecules, particularly through cross-coupling reactions like the Suzuki-Miyaura reaction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in advanced materials science for creating novel functional polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the specific aromatic structure imparts desired biological activity.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for constructing biaryl and heterobiaryl structures, a cornerstone reaction in medicinal and process chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated system and functional handles.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent for creating high-performance polymers and liquid crystalline materials with specific optical and thermal properties.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and inhibitors for biochemical and pharmacological research.

Basic Information

Product Name	2-[(3'-(Trifluoromethyl)Phenoxy)Methyl]Phenylboronic Acid
CAS No.	1072951-60-0
Molecular Formula	C14H12BF3O3
Molecular Weight	296.05 g/mol
Synonyms	[2-[(3-(Trifluoromethyl)phenoxy)methyl]phenyl]boronic acid; 2-[[3-(Trifluoromethyl)phenoxy]methyl]benzeneboronic acid; 2-[(3-Trifluoromethylphenoxy)methyl]phenylboronic Acid; (2-{[3-(Trifluoromethyl)phenoxy]methyl}phenyl)boronic acid; Boronic acid, B-[2-[[3-(trifluoromethyl)phenoxy]methyl]phenyl]-; 1072951-60-0; 2-(3-Trifluoromethylphenoxymethyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity chemical intermediates. Each batch is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a quality management system to ensure batch-to-batch consistency and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.