Description

n-[[2-(Diphenylphosphino)Phenyl]Methylene]-3-Methyl-L-Valine Sodium Salt is a sophisticated chiral ligand and organocatalyst derived from a modified amino acid framework. This compound is valued for its role in facilitating highly selective asymmetric synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in catalytic transformations.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, including hydrogenation, cross-coupling, and hydroformylation.
• Critical component in the asymmetric synthesis of active pharmaceutical ingredients (APIs) and key chiral intermediates.
• Utilized in the development of novel organocatalytic processes for the production of enantiomerically pure compounds.
• Research tool in academic and industrial laboratories for studying and developing new catalytic methodologies.
• Potential application in the synthesis of agrochemicals and specialty chemicals where chirality impacts biological activity.
• Used in the preparation of metal-organic frameworks (MOFs) or complexes for material science applications.

Basic Information

Product Name	n-[[2-(Diphenylphosphino)Phenyl]Methylene]-3-Methyl-L-Valine Sodium Salt
CAS No.	1067225-04-0
Molecular Formula	C27H29NNaO2P
Molecular Weight	453.49 g/mol
Synonyms	Sodium (2S)-3-methyl-2-[[(2-diphenylphosphanylphenyl)methylidene]amino]butanoate; (S)-3-Methyl-2-[[(2-diphenylphosphino)benzylidene]amino]butyric Acid Sodium Salt; L-Valine, N-[[2-(diphenylphosphino)phenyl]methylene]-3-methyl-, sodium salt (1:1); Sodium N-[(2-diphenylphosphanylphenyl)methylidene]-3-methyl-L-valinate; Chiral P,N-Ligand; Valine-derived Schiff Base Ligand Sodium Salt
EINECS	Contact for details

Quality Control

Our production of n-[[2-(Diphenylphosphino)Phenyl]Methylene]-3-Methyl-L-Valine Sodium Salt adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.